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Compounded against brand name, ten routes priced side by side.

By The GLP1 Support team · Last reviewed September 2026

A plain injector pen, a glass vial and a medication carton laid out side by side

The ten routes

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Your own doctor, with insurance

$0 to $25/mo

Price checked September 2026

What ships
Brand pens
Who sets dose
Your doctor

The cheapest route by far for anyone whose plan covers weight management. Also the least predictable, because your plan decides rather than you.

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Research Labs

$29/mo

Price checked September 2026

What ships
Unmixed vials
Who sets dose
You

Lowest advertised cash price on this page. Vials of compound and bacteriostatic water ship separately; you reconstitute and draw your own dose.

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Lttl

$89/mo

Price checked September 2026

What ships
Compounded
Who sets dose
Their clinician

Subscription including supplies and check-ins. Lowest monthly price among the telehealth subscriptions.

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Ro

$149/mo

Price checked September 2026

What ships
Compounded
Who sets dose
Their clinician

Membership fee separate from medication. Will help pursue insurance coverage first.

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Noom Med

$179 to $279/mo

Price checked October 2026

What ships
Compounded
Who sets dose
Their clinician

A behavioural programme with medication attached, rather than medication with support attached. Several programmes at several prices.

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Hims

$199/mo

Price checked September 2026

What ships
Compounded
Who sets dose
Their clinician

Bundled pricing with check-ins. Brand fills priced separately and higher.

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ConciergeMD LA

From $199/mo

Price checked September 2026

What ships
Compounded GLP-1s and peptides
Who sets dose
Their medical team

A concierge medical practice selling compounded semaglutide and tirzepatide injections alongside a wide range of peptide therapies online. Virtual consultation, medication shipped to your home, self-administered.

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Fridays

$279/mo

Price checked September 2026

What ships
Compounded
Who sets dose
Their clinician

Telehealth subscription with medication included. Dose changes reviewed by a clinician.

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LillyDirect

$299 to $449/mo

Price checked October 2026

What ships
Zepbound vials or pens
Who sets dose
Your doctor

Eli Lilly's own self-pay channel for Zepbound. Vials or pens, priced by dose strength rather than flat.

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NovoCare Pharmacy

$349/mo

Price checked October 2026

What ships
Wegovy
Who sets dose
Your doctor

Novo Nordisk's own self-pay channel for Wegovy. One price across dose strengths.

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What actually differs between them

Price is the axis everyone compares on and the least interesting one. These routes differ on five things, and four of them do not appear on a pricing page.

  • What ships. Unmixed vials you reconstitute, a compounded multi-dose vial, or an FDA-approved brand pen. These are genuinely different products.
  • Who sets your dose. Their clinician, your own doctor, or you.
  • What oversight exists. An approved product carries batch testing, inspection and recall machinery. A 503B outsourcing facility carries some of that. A 503A pharmacy carries less. A research vendor carries none.
  • What happens when supply tightens. Brand availability moves with manufacturing. Compounded availability moves with regulatory status, which changes faster and with less notice.
  • Who is responsible when something goes wrong, and whether there is anyone to call.

The questions worth asking any of them

  • Is the medication compounded, and if so at a 503A pharmacy or a 503B outsourcing facility?
  • Is there a batch certificate of analysis from an independent laboratory?
  • Does the price change as my dose escalates?
  • Is this an introductory rate?
  • Is medication included or billed separately from any membership fee?
  • What is the minimum commitment and what does cancelling cost?
  • What happens to my treatment if the product becomes unavailable?

Compounded or brand name: what actually differs · What a year on tirzepatide costs, route by route

What semaglutide costs by channel

Brand, with insurance coverage
Where a plan covers weight management, usually after prior authorisation.
$0–25/mo
Research vendor, unmixed vials
Vials of compound and bacteriostatic water, no prescription and no clinician. You reconstitute and dose yourself.
$29–59/mo
Compounded, telehealth subscription
Priced per month including clinician review. Availability now depends on shortage status.
$89–279/mo
Brand, manufacturer cash programme
The maker's own direct-pay channel, no insurance involved.
$349–499/mo
Brand, retail list price
The number before any coverage, coupon or programme is applied.
$1,300+/mo

Insurance coverage for weight management is inconsistent and often requires prior authorisation.

Educational only. Nothing here is medical advice, and nothing here substitutes for a conversation with a licensed clinician who knows your history. Dosing, side effects and outcomes vary between people.